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In a finding that directly contradicts the standard biological model of animal cell communication, UCSF scientists have discovered that typical cells in animals have the ability to transmit and receive biological signals by making physical contact with each other, even at long distance.
The mechanism is similar to the way neurons communicate with other cells, and contrasts the standard understanding that non-neuronal cells “basically spit out signaling proteins into extracellular fluid and hope they find the right target,” said senior investigator Thomas B. Kornberg, Ph.D., a professor of biochemistry with the UCSF Cardiovascular Research Institute.
The paper was published today (Jan. 2)